Laboratory of Immunology

Areg Totolyan
Head of the Laboratory, MD, Professor

The research is devoted to studying the role of immune, molecular and genetic factors in the development of autoimmune diseases and includes the following: pathological angiogenesis mediators in rheumatoid arthritis, molecular genetic susceptibility to diabetes of 1 type, Basedow’s disease, rheumatoid arthritis, new biological and genetic markers predicting disease course.

Research directions:

• The role of angiogenic and angiostatic chemokines in the pathogenesis of rheumatoid arthritis
• Genetic factors in the development of autoimmune diseases

Key publications of the Division

Zhebrun D., Kudryashova Y., Babenko A., Maslyansky A., Kunitskaya N., Popcova D., Klushina A., Grineva E., Kostareva A., Shlyakhto E.
Association of PTPN22 1858T/T genotype with type 1 diabetes, Graves' disease but not with rheumatoid arthritis in Russian population. Aging. 2011 Apr; 3 (4): 368-73