Research

For more detail on quantitative scientific performance, see the section Science.

In 2022, the Centre obtained 53 intellectual property results, including 21 patents, 16 database certificates and 16 software certificates. Thirty-two invention applications and one utility model application were filed.

Research under grant projects

In 2022, Almazov Centre carried out research under 20 grants including:

• 3 grants from the Ministry of Science and Higher Education of the Russian Federation
• 10 grants from the Russian Science Foundation (RSF)
• 7 grants from the Russian Foundation for Basic Research (RFBR)

The most significant grant project in 2022 was the project to establish and develop a World-Class Research Centre for Personalized Medicine (total funding from the federal budget: more than RUB 2.5 bln).

A total of 134 articles based on the results of research under grant projects were published with a total impact factor of 483.0.

World-class research centre for personalized medicine

In 2022, the WCRC for Personalized Medicine headed by Academician of the Russian Academy of Sciences Evgeny Shlyakhto continued research aimed at developing and implementing diagnostic and treatment technologies based on personalized medicine, including genetic risk assessment, methods of pharmacogenetics and pharmacogenomics, disease biomodelling, genome modification and the creation of drugs for gene therapy and biomedical cell products with the use of genome editing technologies to improve the quality of treatment and reduce mortality in various cardiovascular diseases, metabolic comorbidities, hematological malignancies and certain types of solid tumors, some infectious diseases, as well as in genetic diseases, including rare and understudied ones.

Clinical testing

Medical care at Almazov Centre can be provided as part of clinical testing of prevention, diagnosis, treatment and rehabilitation methods for various diseases (since 2015).

To date, Almazov Centre has tested 208 protocols, 42 of which were developed by its specialists. More than 4,700 patients from all over Russia received medical care. It should be noted that in 2015 only 28 patients took advantage of this opportunity, in 2022 it was 753 patients.

The main areas for clinical testing in 2022 were: obstetrics and gynecology – 287 patients, cardiovascular surgery – 248 patients, neurosurgery – 70 patients, oncology – 52 patients.

Defended theses 

In 2022, a total of 36 theses were successfully defended under the guidance of leading professors and doctors of sciences of Almazov Centre, including 6 doctoral theses and 30 PhD theses.